Author: Hao, Xin-yan; Lv, Qi; Li, Feng-di; Xu, Yan-feng; Gao, Hong
Title: The characteristics of hDPP4 transgenic mice subjected to aerosol MERS coronavirus infection via an animal nose-only exposure device Document date: 2019_10_30
ID: vkjcheaz_51
Snippet: Significantly elevated levels of IL-1β, IL-6, IL-8, IL-10, TNF-α, and IFN-γ were discovered in the lungs and brains of mice in the aerosol group with increased CXCL-1 at 3-9 days (P < .05) postchallenge and in those of mice the instillation group at 3 and 5 days postchallenge ( Figure 6 ). In the aerosol group, the exposed mice showed peak IL-10 and concentration in the lungs and IL-10 and CXCL-1 concentrations in the brain at 5-9 days, and pe.....
Document: Significantly elevated levels of IL-1β, IL-6, IL-8, IL-10, TNF-α, and IFN-γ were discovered in the lungs and brains of mice in the aerosol group with increased CXCL-1 at 3-9 days (P < .05) postchallenge and in those of mice the instillation group at 3 and 5 days postchallenge ( Figure 6 ). In the aerosol group, the exposed mice showed peak IL-10 and concentration in the lungs and IL-10 and CXCL-1 concentrations in the brain at 5-9 days, and peak TNF-α and IFN-γ levels in the lungs and brains with peak IL-6 level at
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