Selected article for: "host response and kinase inhibitor"

Author: Josset, Laurence; Zeng, Hui; Kelly, Sara M.; Tumpey, Terrence M.; Katze, Michael G.
Title: Transcriptomic Characterization of the Novel Avian-Origin Influenza A (H7N9) Virus: Specific Host Response and Responses Intermediate between Avian (H5N1 and H7N7) and Human (H3N2) Viruses and Implications for Treatment Options
  • Document date: 2014_2_4
  • ID: uz0m1o0q_15
    Snippet: Altogether, a combination of two different approaches identified the kinase inhibitor SB-203580 and genistein as capable of reversing the host response to all tested IAVs, including H7N9. Additional molecules identified by both methods as reverting H7N9 signatures were troglitazone, minocycline, and LY-294002......
    Document: Altogether, a combination of two different approaches identified the kinase inhibitor SB-203580 and genistein as capable of reversing the host response to all tested IAVs, including H7N9. Additional molecules identified by both methods as reverting H7N9 signatures were troglitazone, minocycline, and LY-294002.

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