Author: Wang, Shiliang; Sundaram, Jaideep P.; Stockwell, Timothy B.
Title: VIGOR extended to annotate genomes for additional 12 different viruses Document date: 2012_6_4
ID: wd3ir3wg_42
Snippet: Each of the different virus-specific VIGOR programs has also been tested with the viral genomic sequences generated by GSCID at JCVI. All the predictions have been examined by human annotators by comparing the predicted proteins with homologous proteins in GenBank. The evaluation data presented here indicated that VIGOR is not only able to accurately define the start and stop codons of genes in the designated viral genomes, but it can also precis.....
Document: Each of the different virus-specific VIGOR programs has also been tested with the viral genomic sequences generated by GSCID at JCVI. All the predictions have been examined by human annotators by comparing the predicted proteins with homologous proteins in GenBank. The evaluation data presented here indicated that VIGOR is not only able to accurately define the start and stop codons of genes in the designated viral genomes, but it can also precisely identify the complex gene features like RNA editing, stop codon read-through, alternative splicing and alternative translation initiation. Mature peptide prediction function has also been built into VIGOR for some viruses.
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