Author: Dawson, Patrick; Malik, Mamunur Rahman; Parvez, Faruque; Morse, Stephen S.
Title: What Have We Learned About Middle East Respiratory Syndrome Coronavirus Emergence in Humans? A Systematic Literature Review Document date: 2019_3_1
ID: yb54i1ne_97
Snippet: Exposure in most primary cases is still largely inferential at best. While camels are apparently often the likely source, the definitions of camel exposure are varied, preventing clear epidemiological inferences. Definitions of the exposures and the methodology and metrics for determining exposure should be clarified and standardized. Even if camels are a principal source of human infections, this would still not explain a substantial portion of .....
Document: Exposure in most primary cases is still largely inferential at best. While camels are apparently often the likely source, the definitions of camel exposure are varied, preventing clear epidemiological inferences. Definitions of the exposures and the methodology and metrics for determining exposure should be clarified and standardized. Even if camels are a principal source of human infections, this would still not explain a substantial portion of primary human cases that did not have apparent camel exposure before infection. This raises questions about how and where these other primary cases acquired MERS-CoV infection, whether through other animal species, unidentified zoonotic exposure, unrecognized infectious persons (such as asymptomatic infectious individuals), or environmental contamination.
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