Author: Kevin Dick; Kyle K Biggar; James R Green
Title: Computational Prediction of the Comprehensive SARS-CoV-2 vs. Human Interactome to Guide the Design of Therapeutics Document date: 2020_3_31
ID: dxabs45r_38
Snippet: Notably, it is known that the SARS-CoV Spike protein binds to the human ACE2 receptor [19] . Upon entry into the respiratory or gastrointestinal tracts, coronaviruses establish themselves by entering and infecting lumenal macrophages and epithelial cells. The viral cell entry program is orchestrated by the spike protein that binds to the human cellular receptors and, thereby, mediates virus-cell membrane fusions......
Document: Notably, it is known that the SARS-CoV Spike protein binds to the human ACE2 receptor [19] . Upon entry into the respiratory or gastrointestinal tracts, coronaviruses establish themselves by entering and infecting lumenal macrophages and epithelial cells. The viral cell entry program is orchestrated by the spike protein that binds to the human cellular receptors and, thereby, mediates virus-cell membrane fusions.
Search related documents:
Co phrase search for related documents- cell entry and gastrointestinal respiratory tract: 1
- cell entry and human cellular receptor: 1, 2, 3, 4, 5, 6
- cell entry and mediate virus cell membrane fusion: 1, 2, 3, 4
- cell entry and SARS CoV Spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell entry and spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell entry and virus cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell entry and virus cell membrane: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cell entry and virus cell membrane fusion: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cellular receptor and epithelial cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- cellular receptor and gastrointestinal respiratory tract: 1, 2
- cellular receptor and human cellular receptor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cellular receptor and SARS CoV Spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cellular receptor and spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cellular receptor and virus cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- cellular receptor and virus cell membrane: 1, 2, 3, 4, 5, 6, 7
- cellular receptor and virus cell membrane fusion: 1, 2, 3, 4
- epithelial cell and gastrointestinal respiratory tract: 1
- epithelial cell and human cellular receptor: 1
- epithelial cell and SARS CoV Spike protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date