Selected article for: "ARDS treatment and mechanical ventilation"

Author: Chen, Hsing I
Title: Acute lung injury and acute respiratory distress syndrome: experimental and clinical investigations
  • Document date: 2011_3_23
  • ID: xenq90xj_12
    Snippet: The treatment of ARDS/ALI is difficult and complex. Several review articles and monographs have addressed the issue of possible therapeutic regimen. The modalities include extracorporeal membrane oxygenation, prone position, mechanical ventilation with appropriate tidal volume and respiratory pressure, fluid and hemodynamic management and permissive hypercapnic acidosis. [68, 100, [109] [110] [111] [112] [113] [114] [115] [116] [117] [118] [119] .....
    Document: The treatment of ARDS/ALI is difficult and complex. Several review articles and monographs have addressed the issue of possible therapeutic regimen. The modalities include extracorporeal membrane oxygenation, prone position, mechanical ventilation with appropriate tidal volume and respiratory pressure, fluid and hemodynamic management and permissive hypercapnic acidosis. [68, 100, [109] [110] [111] [112] [113] [114] [115] [116] [117] [118] [119] Other pharmacological treatments are anti-inflammatory and/or antimicrobial agents to control infection and to abrogate sepsis, adequate nutrition, surfactant therapy, inhalation of NO and other vasodilators, glucocorticoids and other nonsteroid anti-inflammatory drugs, agents that accelerate lung water resolution and ion transports. [68, 102, [120] [121] [122] [123] [124] Although most animal experimentations on these pharmacological options showed favorable results, the effectiveness and outcomes in clinical studies or trials were conflicting.

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