Author: Morokutti-Kurz, Martina; Graf, Christine; Prieschl-Grassauer, Eva
Title: Amylmetacresol/2,4-dichlorobenzyl alcohol, hexylresorcinol, or carrageenan lozenges as active treatments for sore throat Document date: 2017_2_28
ID: q5j3vcfm_46
Snippet: Different to the findings of Oxford et al, 5 who did not see any virucidal effect on minor group HRV2, we found AMC/ DCBA containing lozenges #3 and #4 to be slightly and highly active against minor group HRV1a, respectively. Lozenge #2, containing HR as active ingredient, was moderately antivirally active. In the case of HRV8, a member of the major group rhinoviruses, the by far largest group of rhinoviruses, we could confirm the findings of Oxf.....
Document: Different to the findings of Oxford et al, 5 who did not see any virucidal effect on minor group HRV2, we found AMC/ DCBA containing lozenges #3 and #4 to be slightly and highly active against minor group HRV1a, respectively. Lozenge #2, containing HR as active ingredient, was moderately antivirally active. In the case of HRV8, a member of the major group rhinoviruses, the by far largest group of rhinoviruses, we could confirm the findings of Oxford et al. 5 None of the tested AMC/DCBA or HR containing lozenges showed any antiviral activity at the testable concentrations. In contrast, lozenge #1 was highly active against HRV1a and HRV8, with 2-to 67.9fold superiority toward all tested other tested lozenges.
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