Author: Kang, Soo Jung; Kim, Nam Su
Title: Association of Toll-like receptor 2-positive monocytes with coronary artery lesions and treatment nonresponse in Kawasaki disease Document date: 2017_7_31
ID: tk1bxztw_46
Snippet: Evidence of the usefulness of TLR expression in monitoring cardiovascular disease burden and severity can be found in the study by Methe et al. 26) , who showed that increased TLR expression levels are involved in the progression of atherosclerotic lesions, demonstrating the expansion of circulating TLR4 + mono cytes in patients with acute coronary syndrome 26) . We suggest, based on our results and the results of Methe et al. 26) , that TLR expr.....
Document: Evidence of the usefulness of TLR expression in monitoring cardiovascular disease burden and severity can be found in the study by Methe et al. 26) , who showed that increased TLR expression levels are involved in the progression of atherosclerotic lesions, demonstrating the expansion of circulating TLR4 + mono cytes in patients with acute coronary syndrome 26) . We suggest, based on our results and the results of Methe et al. 26) , that TLR expression levels could be used to monitor cardiovascular disease burden and severity of KD. Additionally, using whole blood to measure TLR expression requires relatively few steps, suggesting TLR as a potentially easy touse biomarker.
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