Clinicopathologic Features and Magnetic Resonance Imaging Findings in 24 Cats With Histopathologically Confirmed Neurologic Feline Infectious Peritonitis

Crawford, A.H.; Stoll, A.L.; Sanchez-Masian, D.; Shea, A.; Michaels, J.; Fraser, A.R.; Beltran, E.

Of the 10 cases from the RVC, pathologic samples were available for review in 9 cats (2 with a T3-L3 myelopathy, 3 with vestibular syndrome, and 4 with multifocal CNS disease). The 2 cats with a T3-L3 myelopathy had perivascular infiltrates 0-6 cells in thickness, the 3 cats with vestibular syndrome had infiltrates 1-14 cells in thickness, and the 4 cats with multifocal CNS disease had infiltrates 3-20 cells or more in thickness. Extension into the adjacent neuropil surrounding the mesencephalic aqueduct and fourth ventricle was evident in none of the T3-L3 myelopathy group, 2 of the vestibular syndrome group, and 3 of the multifocal CNS disease group. Extension into the neuropil adjacent to the lateral ventricles was evident in 1 cat in the multifocal CNS disease group. Therefore, histopathologic lesion severity was most marked in the multifocal CNS disease group.