Selected article for: "genome sequence and nucleotide sequence"
Author: Fan Wu; Su Zhao; Bin Yu; Yan-Mei Chen; Wen Wang; Yi Hu; Zhi-Gang Song; Zhao-Wu Tao; Jun-Hua Tian; Yuan-Yuan Pei; Ming-Li Yuan; Yu-Ling Zhang; Fa-Hui Dai; Yi Liu; Qi-Min Wang; Jiao-Jiao Zheng; Lin Xu; Edward C. Holmes; Yong-Zhen Zhang
Title: Complete genome characterisation of a novel coronavirus associated with severe human respiratory disease in Wuhan, China
  • Document date: 2020_1_25
    • ID: 5jai745w_3
    Snippet: To determine the evolutionary relationships between WHCV and previously identified 125 coronaviruses, we estimated phylogenetic trees based on the nucleotide sequences of the 126 whole genome sequence, non-structural protein genes ORF1a and 1b, and the main structural The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.01.24.919183 doi: bioRxiv preprint 7 82.3% amino acid (aa) identity (and ~.....
    Document: To determine the evolutionary relationships between WHCV and previously identified 125 coronaviruses, we estimated phylogenetic trees based on the nucleotide sequences of the 126 whole genome sequence, non-structural protein genes ORF1a and 1b, and the main structural The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.01.24.919183 doi: bioRxiv preprint 7 82.3% amino acid (aa) identity (and ~77.2% aa identity to SARS CoV; Table S3 ), while in the 135 ORF1b phylogeny WHCV fell in a basal position within the subgenus Sarbecovirus ( Figure 136 3). This topological division was also observed in the phylogenetic trees estimated for 137 conserved domains in the replicase polyprotein pp1ab ( Figure S5 ).

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