Author: Chang Liu; Ze Chen; Wenyuan Shen; Deshui Yu; Siyu Li; Yue Hu; Haishuo Ji; Wenjun Bu; Qingsong Wang; Shan Gao
Title: Complemented palindrome small RNAs first discovered from SARS coronavirus Document date: 2017_9_7
ID: g55d5ijx_21
Snippet: The read count of siRNA duplexes varies with the duplex length and the overhang length, using data from 312 11 invertebrate viral genomes. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/185876 doi: bioRxiv preprint All the genome sequences are represented by their GenBank accession numbers (e.g. DQ497008). A. 16-nt, 318 18-nt, 19-nt, 20-nt and 22-nt siRNA duplexes were used .....
Document: The read count of siRNA duplexes varies with the duplex length and the overhang length, using data from 312 11 invertebrate viral genomes. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/185876 doi: bioRxiv preprint All the genome sequences are represented by their GenBank accession numbers (e.g. DQ497008). A. 16-nt, 318 18-nt, 19-nt, 20-nt and 22-nt siRNA duplexes were used for RNAi experiments. *16-nt and 20-nt had not 319 been detected in this study. B. All the homologous sequences at the 22-nt locus on civet betacoronavirus 320 genomes were identical to SARS-CoV-cpsR-22, while one of four genotypes at the 22-nt locus on bat 321 betacoronavirus genomes was identical to SARS-CoV-cpsR-22. C. The psRNA (heteropalindromic) hsa-tiR-322 MDL1 and cpsRNA SARS-CoV-cpsR-22 can form hairpins. D. The phylogenetic tree was built by the 323
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