Author: Rogers, J.; Schoepp, R.J.; Schröder, O.; Clements, T.L.; Holland, T.F.; Li, J.Q.; Li, J.; Lewis, L.M.; Dirmeier, R.P.; Frey, G.J.; Tan, X.; Wong, K.; Woodnutt, G.; Keller, M.; Reed, D.S.; Kimmel, B.E.; Tozer, E.C.
Title: Rapid discovery and optimization of therapeutic antibodies against emerging infectious diseases Document date: 2008_5_13
ID: xkx56h0o_68
Snippet: For the best humanized antibody (2978/10), increased affinity correlates with an improved neutralization capacity, however, it is not necessarily the only contributor. It is also possible that there has been a change in the fine specificity of the antibody binding to the spike protein......
Document: For the best humanized antibody (2978/10), increased affinity correlates with an improved neutralization capacity, however, it is not necessarily the only contributor. It is also possible that there has been a change in the fine specificity of the antibody binding to the spike protein.
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