Author: Neethirajan, Suresh; Ahmed, Syed Rahin; Chand, Rohit; Buozis, John; Nagy, Éva
Title: Recent Advances in Biosensor Development for Foodborne Virus Detection Document date: 2017_7_5
ID: sj6zfybb_93
Snippet: Another norovirus RNA detecting biosensor has been developed using a beacon probe conjugated alloyed thioglycolic-capped CdZnSeS quantum dot [101] . A modified silanisation method is applied to encapsulate the thiol-capped quantum dot, leading to a high photo-luminescence quantum yield of 98%. Its sensitivity of detection limit is 8.2 copies/mL. A label-free gold-immobilised synthetic peptide-based electrochemical biosensor is used to detect noro.....
Document: Another norovirus RNA detecting biosensor has been developed using a beacon probe conjugated alloyed thioglycolic-capped CdZnSeS quantum dot [101] . A modified silanisation method is applied to encapsulate the thiol-capped quantum dot, leading to a high photo-luminescence quantum yield of 98%. Its sensitivity of detection limit is 8.2 copies/mL. A label-free gold-immobilised synthetic peptide-based electrochemical biosensor is used to detect noroviruses [102] . The cysteine incorporated recognition peptides and amino acid substituted are isolated from a phage displaying and selecting process. Its sensitivity of detection limit is 99.8 nM for recombinant noroviral capsid proteins; and 7.8 copies/mL for human noroviruses. The concept of affinity peptides as molecular binders can be applied to miniaturised micro-device as a diagnostic tool for POC testing.
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