Title: Research Communications of the 24th ECVIM-CA Congress Document date: 2015_1_10
ID: r59usk02_163
Snippet: Residual samples of citrate anticoagulated blood were used from dogs and cats presented to a specialist referral centre for various reasons unrelated to clotting abnormalities. Initially the blood was stimulated using specific combinations of either arachidonic acid/epinephrine (AA/EPI) or ADP/U46619, designed to assess the effects of the anti-thrombotic agents aspirin and clopidogrel respectively. After 5 minutes stimulation, the blood samples w.....
Document: Residual samples of citrate anticoagulated blood were used from dogs and cats presented to a specialist referral centre for various reasons unrelated to clotting abnormalities. Initially the blood was stimulated using specific combinations of either arachidonic acid/epinephrine (AA/EPI) or ADP/U46619, designed to assess the effects of the anti-thrombotic agents aspirin and clopidogrel respectively. After 5 minutes stimulation, the blood samples were fixed using a patented platelet fixative solution developed for human platelets, which allows the delayed analysis of P-selectin an established marker of platelet activation.
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