RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS

Dogs with history, clinical and clinicopathological signs consistent with iAKI (serum creatinine >1.6 mg/dL and/or urinary output <1ml/kg/h over 6h, in absence of fluid‐responsiveness), as reported by AKI‐IRIS staging guidelines, were prospectively included and grouped according to their aetiological diagnosis in Leptospiral‐iAKI or Other‐iAKI. Leptospirosis was diagnosed by positive microagglutination test (MAT; titre ≥1:800) upon admission or 4‐fold increase in convalescent MAT titre and/or positive qPCR on blood/urine. Routine laboratory analyses, urine chemistry including fractional excretion (FE) of electrolytes (sodium, potassium, magnesium, phosphate, calcium) and urine neutrophil gelatinase‐associated lipocalin (uNGAL), were performed upon admission. Data were reported as median, range (min‐max), and reference interval (R.I.). Groups were compared using non‐parametric statistics (P<0.05 considered significant).