Selected article for: "functional impact and gene expression"

Title: RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS
  • Document date: 2018_12_19
  • ID: r79h9yzz_297
    Snippet: The DM‐associated ACP1 promoter haplotype did not influence gene expression in CHO cells, compared with variant 2, which was more prevalent in non‐diabetic cats. This might be due to a lack of any functional impact of these polymorphisms or the result of the experimental system used. Further experiments are required to assess the functional consequences of ACP1 promoter genetic variability in cells expressing the insulin receptor......
    Document: The DM‐associated ACP1 promoter haplotype did not influence gene expression in CHO cells, compared with variant 2, which was more prevalent in non‐diabetic cats. This might be due to a lack of any functional impact of these polymorphisms or the result of the experimental system used. Further experiments are required to assess the functional consequences of ACP1 promoter genetic variability in cells expressing the insulin receptor.

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