RESEARCH COMMUNICATIONS OF THE 28th ECVIM-CA CONGRESS

Two dogs were excluded because of presence of metastatic malignant lymphoma and pituitary adenoma. In the pituitary glands of the remaining 18 dogs, occasional scattered CD3+ cells were found on immunohistochemistry. The CD3+ CPA differed significantly between parts of the pituitary gland (p < 0.001). The highest CD3+ CPA was found in the pars tuberalis (median CPA 41.3 cells/mm2, range 8.9 to 94.7 cells/mm2). The lowest CD3+ CPA was found in the infundibulum (median CPA 2.0 cells/mm2, range 0 to 10.7 cells/mm2). Only 6 of the 18 dogs (33%) had detectable CD79a+ cells in their pituitary glands, and when present they were in small numbers (median total cell number 0 cells/section, range 0 to 14 cells/section).