Risk factors for severe bronchiolitis caused by respiratory virus infections among Mexican children in an emergency department

Robledo-Aceves, Mireya; Moreno-Peregrina, María de Jesús; Velarde-Rivera, Fernando; Ascencio-Esparza, Elba; Preciado-Figueroa, Francisco M.; Caniza, Miguela A.; Escobedo-Melendez, Griselda

This retrospective, case-controlled study included all children 2 years or younger who were hospitalized with a diagnosis of severe bronchiolitis in the Emergency department at the Civil Hospital of Guadalajara Dr. Juan I. Menchaca from September 2012 to January 2015. Severe bronchiolitis was defined as rhinorrhea, cough, tachypnea, wheezing, rales, and increased respiratory effort (e.g., grunting, nasal flaring, and intercostal and/or subcostal retraction), with symptoms of severity (e.g., increased respiratory rate, retractions, and oxygen saturation at 90% or lower). [25] All these children with severe bronchiolitis-diagnosed were hospitalized in ward. In addition, clinical information about healthy age-matched children, that received care for healthy children control, from the same period of time was used as the control group. Informed consent was obtained from the children's parents at the time of clinical evaluation. The Research Council and Ethical Committee of the Civil Hospital of Guadalajara Dr. Juan I. Menchaca approved the study in accordance with the Declaration of Helsinki 1975, as revised in 1983.