Author: He, Jiayang; Li, Zhengtu; Huang, Wanyi; Guan, Wenda; Ma, Hongxia; Yang, Zi feng; Wang, Xinhua
Title: Efficacy and safety of Chou-Ling-Dan granules in the treatment of seasonal influenza via combining Western and traditional Chinese medicine: protocol for a multicentre, randomised controlled clinical trial Document date: 2019_4_2
ID: vn9e5nm3_67
Snippet: The primary and secondary outcomes and safety indicators will be used to evaluate the efficacy and The clinical medicines used for the treatment and prevention of influenza are mainly M2 ion 77 channel blockers (for example, amantadine and rimantadine) and neuraminidase (NA) inhibitors 78 (for example, oseltamivir and zanamivir) 6,7 . Amantadine, however, is prone to drug resistance and 79 is only effective against the influenza A virus 8 . In ad.....
Document: The primary and secondary outcomes and safety indicators will be used to evaluate the efficacy and The clinical medicines used for the treatment and prevention of influenza are mainly M2 ion 77 channel blockers (for example, amantadine and rimantadine) and neuraminidase (NA) inhibitors 78 (for example, oseltamivir and zanamivir) 6,7 . Amantadine, however, is prone to drug resistance and 79 is only effective against the influenza A virus 8 . In addition, the treatment efficiency of amantadine is lower than that of the NA inhibitors. Therefore, amantadine is not recommended routinely for the antibacterial, anti-inflammatory and clearing heat-toxicity effects. The root, or the whole plant, has 110 been widely been used to treat colds, sore throat, bronchitis, malaria and other diseases 18 . system. To develop CLD into a targeted drug with less side effects that can be widely used in the 130 prevention and treatment of influenza, an in-depth study needs to be conducted.
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