Author: Pedersen, Niels C; Kim, Yunjeong; Liu, Hongwei; Galasiti Kankanamalage, Anushka C; Eckstrand, Chrissy; Groutas, William C; Bannasch, Michael; Meadows, Juliana M; Chang, Kyeong-Ok
Title: Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis Document date: 2017_9_13
ID: y13gz4wz_1
Snippet: Drugs that directly inhibit virus replication have become mainstays in the treatment of chronic viral infections such as HIV/AIDS, 1 hepatitis C virus (HCV), 2 hepatitis B virus, herpesvirus and acute infections such as influenza. RNA viruses such as HIV-1 and HCV possess ideal targets for virus inhibition such as RNA-dependent RNA polymerase and protease. Proteases are a particularly good target because they are involved in virus maturation (HIV.....
Document: Drugs that directly inhibit virus replication have become mainstays in the treatment of chronic viral infections such as HIV/AIDS, 1 hepatitis C virus (HCV), 2 hepatitis B virus, herpesvirus and acute infections such as influenza. RNA viruses such as HIV-1 and HCV possess ideal targets for virus inhibition such as RNA-dependent RNA polymerase and protease. Proteases are a particularly good target because they are involved in virus maturation (HIV) or production of functional viral proteins (HCV). Protease inhibitors are also used in combination with inhibitors of reverse transcription for HIV/AIDS for lifelong therapy, and combinations of different
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