Selected article for: "breath shortness cough and cough fever"
Author: Jin, Xi; Lian, Jiang-Shan; Hu, Jian-Hua; Gao, Jianguo; Zheng, Lin; Zhang, Yi-Min; Hao, Shao-Rui; Jia, Hong-Yu; Cai, Huan; Zhang, Xiao-Li; Yu, Guo-Dong; Xu, Kai-Jin; Wang, Xiao-Yan; Gu, Jue-Qing; Zhang, Shan-Yan; Ye, Chan-Yuan; Jin, Ci-Liang; Lu, Ying-Feng; Yu, Xia; Yu, Xiao-Peng; Huang, Jian-Rong; Xu, Kang-Li; Ni, Qin; Yu, Cheng-Bo; Zhu, Biao; Li, Yong-Tao; Liu, Jun; Zhao, Hong; Zhang, Xuan; Yu, Liang; Guo, Yong-Zheng; Su, Jun-Wei; Tao, Jing-Jing; Lang, Guan-Jing; Wu, Xiao-Xin; Wu, Wen-Rui; Qv, Ting-Ting; Xiang, Dai-Rong; Yi, Ping; Shi, Ding; Chen, Yanfei; Ren, Yue; Qiu, Yun-Qing; Li, Lan-Juan; Sheng, Jifang; Yang, Yida
Title: Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms
  • Document date: 2020_3_24
    • ID: zph6r4il_31
    Snippet: The national spread and global sporadic appearance of SARS-CoV-2 have become an enormous threat to human beings, and the threat is not restricted to China. An endeavour has been made by scientists to reveal the epidemiological, clinical and virological characteristics of SARS-CoV-2 with over 30 publications published in PubMed by 5 February 2020. 2 4-7 Nevertheless, most of these studies focused on the situation in Wuhan, China. In addition, the .....
    Document: The national spread and global sporadic appearance of SARS-CoV-2 have become an enormous threat to human beings, and the threat is not restricted to China. An endeavour has been made by scientists to reveal the epidemiological, clinical and virological characteristics of SARS-CoV-2 with over 30 publications published in PubMed by 5 February 2020. 2 4-7 Nevertheless, most of these studies focused on the situation in Wuhan, China. In addition, the initiative for SARS-CoV-2 screening started from fever clinics, while fever, cough and shortness of breath were the most emphasised symptoms, which increases the risk of omitting those patients with other symptoms and normal body temperature. It is theoretically plausible that one characteristic of a viral spread is an increased transmission capacity at the cost of decreased virulence, which is also true for SARS-CoV-2. 15 Therefore, caution should be exercised for suspected patients with COVID-19 who had normal body temperatures and visited various outpatient clinics for non-respiratory symptoms. The suspected patients with COVID-19 with GI symptoms, such as nausea, vomiting and diarrhoea, should be seriously considered, since accumulated evidence supports SARS-CoV-2 transmission through faeces 11 and tears 16 and its ability to bind to ACE2 of the GI tract has been identified. 9 12 In this study, we reported the epidemiological, clinical and virological features of 74 patients with COVID-19 with GI symptoms from Zhejiang province. To our knowledge, this is the first report that describes the situation of patients with COVID-19 GI symptoms and is the largest group of cases outside Wuhan. Our novel findings are valuable for disease prevention by emphasising suspected patients with COVID-19 with GI symptoms and their specific clinical characteristics.

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