Author: Makino, Jun; Koshy, Sanjana; Bajaj, Sonal; Jeong, Young-Gwang; Perlman, David C.
Title: Fulminant ecchymosis as the initial manifestation of antiphospholipid syndrome (APS) triggered by respiratory syncytial virus (RSV) infection: A case report and review of the literature Document date: 2016_11_24
ID: v5ow4jlc_12
Snippet: The presence of multiple ecchymoses, unexplained intermittent fever, joint swelling and weight loss for several months led to the consideration of other rheumatologic diseases, such as rheumatoid arthritis, vasculitis and specifically systemic lupus erythematosus (SLE). The American College of Rheumatology recommends that 4 or more of the 11 proposed criteria are present to identify patients with SLE [13] . However, our patient did not meet the d.....
Document: The presence of multiple ecchymoses, unexplained intermittent fever, joint swelling and weight loss for several months led to the consideration of other rheumatologic diseases, such as rheumatoid arthritis, vasculitis and specifically systemic lupus erythematosus (SLE). The American College of Rheumatology recommends that 4 or more of the 11 proposed criteria are present to identify patients with SLE [13] . However, our patient did not meet the diagnostic criteria for any of these diseases and only met two of the criteria for SLEa positive immunologic disorder and a positive antinuclear antibody. Instead, a positive lupus anticoagulant 65 (normal range: 27-41 s) and cardiolipin Ab IgM 18 (normal range: 0-12) both repeated after 3 months' of discharge from the hospital further supported the diagnosis of APS.
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