Selected article for: "binding site and receptor binding site"
Author: Peña, José; Chen-Harris, Haiyin; Allen, Jonathan E.; Hwang, Mona; Elsheikh, Maher; Mabery, Shalini; Bielefeldt-Ohmann, Helle; Zemla, Adam T.; Bowen, Richard A.; Borucki, Monica K.
Title: Sendai virus intra-host population dynamics and host immunocompetence influence viral virulence during in vivo passage
  • Document date: 2016_4_9
    • ID: z7f720dj_66
    Snippet: Structural comparisons of HN proteins of Paramyxoviridae (hPIV3, Simian PIV5, NDV, Nipah, Hendra) showed strong conformational similarities (above 60% of structure similarity measured by LGA_S score (Zemla 2003) ) even for proteins with sequence identity as low as 21% (Fig. 7) ). The strongest structural similarity was seen in conserved regions forming the neuraminidases six-bladed beta-propeller fold, with some deviations observed in more expose.....
    Document: Structural comparisons of HN proteins of Paramyxoviridae (hPIV3, Simian PIV5, NDV, Nipah, Hendra) showed strong conformational similarities (above 60% of structure similarity measured by LGA_S score (Zemla 2003) ) even for proteins with sequence identity as low as 21% (Fig. 7) ). The strongest structural similarity was seen in conserved regions forming the neuraminidases six-bladed beta-propeller fold, with some deviations observed in more exposed loop regions. The receptor-binding site is located in the center of the propeller.

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