Author: Zheng, Li-Zhen; Wang, Jia-Li; Kong, Ling; Huang, Le; Tian, Li; Pang, Qian-Qian; Wang, Xin-Luan; Qin, Ling
Title: Steroid-associated osteonecrosis animal model in rats Document date: 2018_2_6
ID: tad9jmfp_45
Snippet: In conclusion, the present study successfully induced SAON in a rat model with pulsed injection of LPS and MPS and evaluation protocols with typical histopathologic ON features and advanced evaluation approaches to identify the metabolic disorders of SAON. The SAON rat model is a suitable and cost-effective animal model to study cellular and molecular mechanism of SAON and potential drugs to be developed for prevention and treatment of SAON......
Document: In conclusion, the present study successfully induced SAON in a rat model with pulsed injection of LPS and MPS and evaluation protocols with typical histopathologic ON features and advanced evaluation approaches to identify the metabolic disorders of SAON. The SAON rat model is a suitable and cost-effective animal model to study cellular and molecular mechanism of SAON and potential drugs to be developed for prevention and treatment of SAON.
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