Systems Biology-Based Platforms to Accelerate Research of Emerging Infectious Diseases

Oh, Soo-Jin; Choi, Young-Ki; Shin, Ok Sarah

Emerging infectious diseases (EIDs) are defined as newly appearing infections in a population or diseases that have previously existed, but are rapidly emerging in incidence or geographic range. 1, 2 EIDs are often initiated by pathogens with a change in pathogenicity, and these emerging pathogens are highly likely to be zoonotic, with a broad range of hosts or vector-borne. [3] [4] [5] New human pathogens are especially likely to continue emerging, mainly from mammals and birds, for the foreseeable future. For these reasons, an effective global surveillance system for novel pathogens is needed. Due to the diverse nature of antigenic variation of emerging pathogens and their various strategies to evade the immune system, EIDs continue to pose difficult challenges to clinicians, public health profes-sionals, and researchers globally.