Selected article for: "disease infection and transmission mode"
Author: Oh, Soo-Jin; Choi, Young-Ki; Shin, Ok Sarah
Title: Systems Biology-Based Platforms to Accelerate Research of Emerging Infectious Diseases
  • Document date: 2018_3_1
    • ID: ta5y54lu_12
    Snippet: MERS-CoV infection is a respiratory disease caused by MERS-CoV, a positive single stranded RNA virus. 46 Although the detailed mode of transmission and period of virus shedding from infected patients are not fully understood, a nosocomial infection process is anticipated as the main transmission process. 47 MERS-CoV was first identified in the Middle East where dromedary camels were found to carry MERS-CoV without any respiratory symptoms. 48 The.....
    Document: MERS-CoV infection is a respiratory disease caused by MERS-CoV, a positive single stranded RNA virus. 46 Although the detailed mode of transmission and period of virus shedding from infected patients are not fully understood, a nosocomial infection process is anticipated as the main transmission process. 47 MERS-CoV was first identified in the Middle East where dromedary camels were found to carry MERS-CoV without any respiratory symptoms. 48 The fatality rate of MERS-CoV infection in humans is approximately 20−50%, and its symptoms include fever, cough, and breathing difficulties. 48 Since 2012, about 30 countries, including Saudi Arabia, China, Malaysia, and Jordan, have reported MERS outbreaks, with Saudi Arabia reporting approximately 80% of all outbreaks. 49 Surprisingly, South Korea, which is a non-endemic area for MERS, experienced MERS outbreaks in 2015. 26 It is thought that a traveler returning from Bahrain carrying the MERS virus caused an outbreak of 186 cases and 36 deaths, which had a substantial impact on the South Korean economy. 26 Given the continuum of emergence and the large magnitude of MERS outbreaks in various regions, further studies are required to bolster capabilities for timely detection and effective control and prevention of MERS-CoV.

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