Selected article for: "cellular response and innate immune system"
Author: Nicholls, John M
Title: The Battle Between Influenza and the Innate Immune Response in the Human Respiratory Tract
  • Document date: 2013_3_29
    • ID: vyci1ho3_6
    Snippet: The interaction of influenza with the innate immune defence system mechanism occurs broadly in 2 phases -the first is a circumvention of the natural extracellular host barriers and the second is a hijacking of the intracellular pathways by the virus in order to prevent an antiviral response and direct the cellular machinery towards replication of viral progeny. There are three barriers that influenza needs to defeat in order to successfully infec.....
    Document: The interaction of influenza with the innate immune defence system mechanism occurs broadly in 2 phases -the first is a circumvention of the natural extracellular host barriers and the second is a hijacking of the intracellular pathways by the virus in order to prevent an antiviral response and direct the cellular machinery towards replication of viral progeny. There are three barriers that influenza needs to defeat in order to successfully infect epithelial cells -mucin, host defence lectins and alveolar macrophages.

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