Author: Hu, Yongwu; Wen, Jie; Tang, Lin; Zhang, Haijun; Zhang, Xiaowei; Li, Yan; Wang, Jing; Han, Yujun; Li, Guoqing; Shi, Jianping; Tian, Xiangjun; Jiang, Feng; Zhao, Xiaoqian; Wang, Jun; Liu, Siqi; Zeng, Changqing; Wang, Jian; Yang, Huanming
Title: The M Protein of SARS-CoV: Basic Structural and Immunological Properties Document date: 2016_11_28
ID: xzlcyn3l_16
Snippet: Previously published experimental results and bioinformatics predictions have provided strong evidence that the M protein found in other coronaviruses is a structural membrane protein (4). The M protein of SARS-CoV demonstrates relatively high homology at the amino acid sequence level with its orthologues in Coronaviridae. The high similarity of the M proteins in primary (that is, amino acid sequence) and secondary structure suggests the phylogen.....
Document: Previously published experimental results and bioinformatics predictions have provided strong evidence that the M protein found in other coronaviruses is a structural membrane protein (4). The M protein of SARS-CoV demonstrates relatively high homology at the amino acid sequence level with its orthologues in Coronaviridae. The high similarity of the M proteins in primary (that is, amino acid sequence) and secondary structure suggests the phylogenetic relationship between SARS-CoV and other members of Coronaviridae, conservativeness in evolution, and its importance to the survival of the virus.
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