Author: Hu, Yongwu; Wen, Jie; Tang, Lin; Zhang, Haijun; Zhang, Xiaowei; Li, Yan; Wang, Jing; Han, Yujun; Li, Guoqing; Shi, Jianping; Tian, Xiangjun; Jiang, Feng; Zhao, Xiaoqian; Wang, Jun; Liu, Siqi; Zeng, Changqing; Wang, Jian; Yang, Huanming
Title: The M Protein of SARS-CoV: Basic Structural and Immunological Properties Document date: 2016_11_28
ID: xzlcyn3l_2
Snippet: The M (membrane) protein (also known as E1 membrane glycoprotein or matrix protein) is one of major membrane proteins of the coronavirus together with the S (spike) and the E (envelope) proteins (2). It has been postulated that the M protein is related to viral infectivity through binding to the viral S protein and the host surface receptor(s), thus promoting membrane fusion 1., 3.. It appears to be involved in the antigenicity demonstrated by th.....
Document: The M (membrane) protein (also known as E1 membrane glycoprotein or matrix protein) is one of major membrane proteins of the coronavirus together with the S (spike) and the E (envelope) proteins (2). It has been postulated that the M protein is related to viral infectivity through binding to the viral S protein and the host surface receptor(s), thus promoting membrane fusion 1., 3.. It appears to be involved in the antigenicity demonstrated by the virus-induced immune responses of the host. As the most abundant protein in the virion of coronaviruses, the M protein may also be one of the key components in viral assembly and morphogenesis, involved in regulation of replication and packing the genomic RNA into viral particles 4., 5..
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