Author: Lee, Mi Suk; Oh, Jee Youn; Kang, Cheol-In; Kim, Eu Suk; Park, Sunghoon; Rhee, Chin Kook; Jung, Ji Ye; Jo, Kyung-Wook; Heo, Eun Young; Park, Dong-Ah; Suh, Gee Young; Kiem, Sungmin
Title: Guideline for Antibiotic Use in Adults with Community-acquired Pneumonia Document date: 2018_6_26
ID: sl4u8e6e_237
Snippet: lyzed inpatients with community-acquired pneumonia, repeated CRP measurement at three or four days of treatment helped identify patients at risk of treatment failure or at increased risk of complications [203] [204] [205] [206] . CRP levels >10 mg/dL at four days of treatment were significantly associated with the incidence of complications [207] . On the other hand, patients with CRP levels <3 mg/dL at three days after treatment were at low risk.....
Document: lyzed inpatients with community-acquired pneumonia, repeated CRP measurement at three or four days of treatment helped identify patients at risk of treatment failure or at increased risk of complications [203] [204] [205] [206] . CRP levels >10 mg/dL at four days of treatment were significantly associated with the incidence of complications [207] . On the other hand, patients with CRP levels <3 mg/dL at three days after treatment were at low risk of complications [205] . In addition, patients whose CRP levels did not decrease by over 50% at four days of treatment had a higher 30-day mortality rate, higher risk of ventilator and vasopressor use, and higher risk of complications of pneumonia such as pyothorax [204] . Therefore, although repeated CRP measurement is not significantly beneficial in clinical aspects for patients whose symptoms are worsening, CRP monitoring may help identify patients at risk of treatment failure or complications among those who do not show clear signs of clinical improvements or worsening in the early period of hospitalization.
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