Author: Lang, Dorothy M.; Zemla, A. T.; Zhou, C. L. Ecale
Title: Highly similar structural frames link the template tunnel and NTP entry tunnel to the exterior surface in RNA-dependent RNA polymerases Document date: 2012_12_25
ID: s90geszi_111
Snippet: Structure-based sequence alignment using the StralSV algorithm (1) enabled us to identify seven distinct homologous structures in most of the polymerases in our collection of 22 species. In the RdRps, the combined regions of structural homology represent $75% of the sequence from the start of homomorph of Motif G (hmG) through the end of hmE in each species ($375 residues). There is <10% conservation of sequence composition among these species......
Document: Structure-based sequence alignment using the StralSV algorithm (1) enabled us to identify seven distinct homologous structures in most of the polymerases in our collection of 22 species. In the RdRps, the combined regions of structural homology represent $75% of the sequence from the start of homomorph of Motif G (hmG) through the end of hmE in each species ($375 residues). There is <10% conservation of sequence composition among these species.
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