Title: The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope Document date: 1992_12_2
ID: vznqgnzd_44
Snippet: The sorting determinants in gp210's CT, albeit apparently weaker than those of the TM, are likely to be relevant. If gp210 were to form homodimers via the TM, this could spa- Figure 6 . The CT of gp210 also contains a pore membrane targeting signal. The chimeric protein CD8/gpCT (see Fig. 1 ) was expressed in 3T3 cells and double immunofluorescence was performed, as described in Fig. 4 , to visualize the chimeric protein (mAb anti-CD8, B) and por.....
Document: The sorting determinants in gp210's CT, albeit apparently weaker than those of the TM, are likely to be relevant. If gp210 were to form homodimers via the TM, this could spa- Figure 6 . The CT of gp210 also contains a pore membrane targeting signal. The chimeric protein CD8/gpCT (see Fig. 1 ) was expressed in 3T3 cells and double immunofluorescence was performed, as described in Fig. 4 , to visualize the chimeric protein (mAb anti-CD8, B) and pore complexes (mAb 414, A). Also shown is the distribution pattern of the CDg/E19 chimeric protein within a separate cell (C).
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