Selected article for: "cytoplasm nucleus and host cell"
Author: Wang, Jingqiang; Ji, Jia; Ye, Jia; Zhao, Xiaoqian; Wen, Jie; Li, Wei; Hu, Jianfei; Li, Dawei; Sun, Min; Zeng, Haipan; Hu, Yongwu; Tian, Xiangjun; Tan, Xuehai; Xu, Ningzhi; Zeng, Changqing; Wang, Jian; Bi, Shengli; Yang, Huanming
Title: The Structure Analysis and Antigenicity Study of the N Protein of SARS-CoV
  • Document date: 2016_11_28
    • ID: s38k8d3l_18
    Snippet: Localization to the nucleolus is a common feature of coronavirus N proteins. This feature helps with disrupting host cell division to promote virus assembly and sequestering ribosomes for translation of viral proteins (10). It has been reported that the SR domain in SR proteins is a nuclear localization signal but not a subnuclear speckle one (8). Consequently, the SR-rich region may function only as a nuclear localization signal. Subnuclear loca.....
    Document: Localization to the nucleolus is a common feature of coronavirus N proteins. This feature helps with disrupting host cell division to promote virus assembly and sequestering ribosomes for translation of viral proteins (10). It has been reported that the SR domain in SR proteins is a nuclear localization signal but not a subnuclear speckle one (8). Consequently, the SR-rich region may function only as a nuclear localization signal. Subnuclear localization of the N protein might need several additive and redundant signals. InterproScan has revealed that there is a bipartite nuclear localization signal domain (NLS-BP, IPR001472) in the N protein, which has a sequence of KKKKTDEAQPLPQRQKKQ at Codons 373-390. NLS-BP is a domain for the protein translocation from cytoplasm to nucleus.

    Search related documents:
    Co phrase search for related documents
    • common feature and nuclear localization: 1, 2
    • common feature and nuclear localization signal: 1, 2
    • host cell and nuclear localization: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • host cell and nuclear localization signal: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • host cell and nuclear localization signal domain: 1
    • host cell and nucleolus localization: 1
    • host cell and protein translocation: 1, 2, 3, 4, 5, 6, 7, 8
    • host cell and signal domain: 1, 2, 3, 4, 5, 6
    • host cell and SR protein: 1, 2, 3
    • host cell division and nuclear localization: 1
    • nuclear localization and protein translocation: 1, 2, 3, 4, 5, 6
    • nuclear localization and signal domain: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • nuclear localization and SR domain: 1
    • nuclear localization and SR protein: 1
    • nuclear localization signal and protein translocation: 1, 2, 3
    • nuclear localization signal and signal domain: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • nuclear localization signal domain and protein translocation: 1
    • nuclear localization signal domain and signal domain: 1, 2, 3, 4, 5, 6, 7
    • nucleolus localization and SR protein: 1