Author: Seemann, Stefan E.; Gorodkin, Jan; Backofen, Rolf
Title: Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments Document date: 2008_10_4
ID: wtvfow2f_30
Snippet: For specific cases where there are many additional constraints imposed on the structure, it is a good strategy to identify the reliably conserved substructure rel first, and then search for the consensus structure that maximizes ex-overðÞ and contains rel as a substructure. Reliably conserved substructures are easily integrated into the earlier described Nussinov-style algorithm by setting the weighting factor of thermodynamic overlap to zero i.....
Document: For specific cases where there are many additional constraints imposed on the structure, it is a good strategy to identify the reliably conserved substructure rel first, and then search for the consensus structure that maximizes ex-overðÞ and contains rel as a substructure. Reliably conserved substructures are easily integrated into the earlier described Nussinov-style algorithm by setting the weighting factor of thermodynamic overlap to zero in Equation ( 2) (see Supplementary Material for details).
Search related documents:
Co phrase search for related documents- consensus structure and Nussinov style algorithm: 1, 2
- consensus structure and Supplementary Material: 1
- consensus structure and thermodynamic overlap: 1
- detail Supplementary Material and Supplementary Material: 1
- good strategy and Supplementary Material: 1
- Nussinov style and Supplementary Material: 1
Co phrase search for related documents, hyperlinks ordered by date