Selected article for: "alphavirus veev and codon read"
Author: Wang, Shiliang; Sundaram, Jaideep P.; Stockwell, Timothy B.
Title: VIGOR extended to annotate genomes for additional 12 different viruses
  • Document date: 2012_6_4
    • ID: wd3ir3wg_32
    Snippet: A total of 478 genes in 240 VEEV and alphavirus genomes were detected by VIGOR, and all of them were the same as the annotations in GenBank (table 1) . The stop codon read-through was also detected accurately by VIGOR and a longer protein was generated. Only a small number of genomes of these two viruses have the mature peptides annotated in GenBank. Therefore, the conserved mature peptide cleavage sites (9) were used to evaluate the accuracy of .....
    Document: A total of 478 genes in 240 VEEV and alphavirus genomes were detected by VIGOR, and all of them were the same as the annotations in GenBank (table 1) . The stop codon read-through was also detected accurately by VIGOR and a longer protein was generated. Only a small number of genomes of these two viruses have the mature peptides annotated in GenBank. Therefore, the conserved mature peptide cleavage sites (9) were used to evaluate the accuracy of the VIGOR predictions. All mature peptide sequences predicted by VIGOR were found to be accurate during inspection by human annotators (data not shown).

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