Title: In vitro analysis of the oligodendrocyte lineage in mice during demyelination and remyelination Document date: 1990_9_1
ID: vr5hnzp8_33
Snippet: FGF is also mitogenic for O-2A lineage cells (Eccleston and Silberberg, 1985; Noble et al., 1988; Besnard et al., 1989) . Both FGF and epidermal growth factor inhibit expression of myelin components (Sheng et al., 1989) . IGF-I promotes proliferation of O-2A lineage cells while also inducing precursor cells to develop into oligodendrocytes (McMorris and Dubois-Daicq, 1988) . A protein closely related to ciliary neurotrophic factor is present in d.....
Document: FGF is also mitogenic for O-2A lineage cells (Eccleston and Silberberg, 1985; Noble et al., 1988; Besnard et al., 1989) . Both FGF and epidermal growth factor inhibit expression of myelin components (Sheng et al., 1989) . IGF-I promotes proliferation of O-2A lineage cells while also inducing precursor cells to develop into oligodendrocytes (McMorris and Dubois-Daicq, 1988) . A protein closely related to ciliary neurotrophic factor is present in developing optic nerve and induces transient expression of GFAP in O-2A progenitor cells in vitro Lillien et al., 1988) .
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