Selected article for: "death cause and major cause"
Author: Linder, Kathleen A; McDonald, Philip J; Kauffman, Carol A; Revankar, Sanjay G; Chandrasekar, Pranatharthi H; Miceli, Marisa H
Title: Infectious Complications After Umbilical Cord Blood Transplantation for Hematological Malignancy
  • Document date: 2019_2_22
    • ID: qu20hqch_42
    Snippet: Invasive mold infections were a major cause of death in our cohort, but invasive Candida infections were rare; only 1 patient had 2 episodes of candidemia. The widespread use of azoles for prophylaxis for allogeneic HCT recipients likely has changed the epidemiology of invasive fungal infections in this population [19, 38] . The 4 patients in our cohort who died of invasive aspergillosis did so before neutrophil engraftment, and none were receivi.....
    Document: Invasive mold infections were a major cause of death in our cohort, but invasive Candida infections were rare; only 1 patient had 2 episodes of candidemia. The widespread use of azoles for prophylaxis for allogeneic HCT recipients likely has changed the epidemiology of invasive fungal infections in this population [19, 38] . The 4 patients in our cohort who died of invasive aspergillosis did so before neutrophil engraftment, and none were receiving prophylaxis with a mold-active azole. This high burden of disease early after UCBT underscores the need for aggressive surveillance for fungal infections and the need for mold-active azole prophylaxis.

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