Author: Ma, J; Wan, J; Meng, J; Banerjee, S; Ramakrishnan, S; Roy, S
Title: Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor Document date: 2014_3_6
ID: wu2mogfa_8
Snippet: We also examined LAMP1 which is an integral glycoprotein residing in late endosomes and lysosomes. 14 HUVECs were transfected with lysosomal-associated membrane protein 1green fluorescent protein (LAMP1-GFP) and then treated with vehicle or METH. In Figure 1g we show increased LAMP1-GFP-labeled vesicles in METH-treated HUVECs after 24 and 48 h, indicating induction of an autophagic response following 1 mM METH treatment......
Document: We also examined LAMP1 which is an integral glycoprotein residing in late endosomes and lysosomes. 14 HUVECs were transfected with lysosomal-associated membrane protein 1green fluorescent protein (LAMP1-GFP) and then treated with vehicle or METH. In Figure 1g we show increased LAMP1-GFP-labeled vesicles in METH-treated HUVECs after 24 and 48 h, indicating induction of an autophagic response following 1 mM METH treatment.
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