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Author: Gunn, Michael D.; Kyuwa, Shigeru; Tam, Carmen; Kakiuchi, Terutaka; Matsuzawa, Akio; Williams, Lewis T.; Nakano, Hideki
Title: Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization
  • Document date: 1999_2_1
  • ID: sz28ar3t_18
    Snippet: To determine if the decreased accumulation of DCs in the LNs of plt mice was secondary to a decreased number of resident skin DCs, abdominal epidermis of Ï©/Ï© and plt mice was stained with anti-I-A (Fig. 5, A and B) . There was no significant difference in the density, morphology, or distribution of I-A Ï© DCs in the epidermis of untreated plt and Ï©/Ï© mice. The average number of I-A Ï© epidermal cells in Ï©/Ï© mice was 14 Ï® 2.1 per high power.....
    Document: To determine if the decreased accumulation of DCs in the LNs of plt mice was secondary to a decreased number of resident skin DCs, abdominal epidermis of Ï©/Ï© and plt mice was stained with anti-I-A (Fig. 5, A and B) . There was no significant difference in the density, morphology, or distribution of I-A Ï© DCs in the epidermis of untreated plt and Ï©/Ï© mice. The average number of I-A Ï© epidermal cells in Ï©/Ï© mice was 14 Ï® 2.1 per high power field (HPF) compared with 15.5 Ï® 2.8 in plt mice.

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