Selected article for: "bacterial infection and influenza pandemic"
Author: Cunha, Cheston B; Opal, Steven M
Title: Middle East respiratory syndrome (MERS): A new zoonotic viral pneumonia
  • Document date: 2014_8_15
    • ID: zqnibnf7_15
    Snippet: MERS is a viral pneumonia with rapidly progressive respiratory failure leading to ARDS. As with severe pandemic influenza (H 1 N 1 ), and severe avian influenza (H 7 N 9 ) death is due to hypoxemia from acute respiratory failure. [14] [15] [16] Like SARS and avian influenza (H 7 N 9 ), MERS has not been complicated by bacterial co-infections. 5, [28] [29] [30] Pandemic influenza, in contrast, which may be complicated by simultaneous bacterial co-.....
    Document: MERS is a viral pneumonia with rapidly progressive respiratory failure leading to ARDS. As with severe pandemic influenza (H 1 N 1 ), and severe avian influenza (H 7 N 9 ) death is due to hypoxemia from acute respiratory failure. [14] [15] [16] Like SARS and avian influenza (H 7 N 9 ), MERS has not been complicated by bacterial co-infections. 5, [28] [29] [30] Pandemic influenza, in contrast, which may be complicated by simultaneous bacterial co-infection, with S. aureus (MSSA or MRSA), or sequential co-infection in patients who improve ~1 wk who then may develop a secondary bacterial pneumonia due to Haemophilus influenzae or S. pneumoniae. 14, 15 Since any patient, including MERS or influenza patients, that receive prolonged mechanical ventilation may develop late nosocomial bacterial pneumonia. 5 These are not co-infections, per se, but rather are nosocomial complications of mechanical ventilation. Like pandemic influenza, MERS mortality can be high in normal young adults, but mortality is highest in those with comorbidities. 5

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