Author: Sato, Hiroki; Yoneda, Misako; Honda, Tomoyuki; Kai, Chieko
Title: Morbillivirus Receptors and Tropism: Multiple Pathways for Infection Document date: 2012_3_1
ID: xic32wxh_10
Snippet: Measles virus was first isolated by Enders and Peebles (1954) from primary human kidney cells inoculated with the blood and throat washings of a child with measles. The virus strain (Edmonston) was passaged multiple times in primary human kidney and amnion cells and then adapted to eggs and multiply passaged in chick embryo cells to produce the original Edmonston B vaccine, which was licensed in 1963 (Griffin, 2007) . Administration of the live a.....
Document: Measles virus was first isolated by Enders and Peebles (1954) from primary human kidney cells inoculated with the blood and throat washings of a child with measles. The virus strain (Edmonston) was passaged multiple times in primary human kidney and amnion cells and then adapted to eggs and multiply passaged in chick embryo cells to produce the original Edmonston B vaccine, which was licensed in 1963 (Griffin, 2007) . Administration of the live attenuated vaccine results in transient immunosuppression, but induces both expression of the neutralizing antibody and cellular immune responses sufficient for protection.
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