Selected article for: "dose dependent manner and present study"
Author: Wu, Beibei; Wang, Liyin; Jiang, Lili; Dong, Lili; Xu, Fengli; Lu, Yili; Jin, Jiahui; Wang, Zhanyue; Liang, Guang; Shan, Xiaoou
Title: n-butanol extract from Folium isatidis inhibits the lipopolysaccharide-induced downregulation of CXCR1 and CXCR2 on human neutrophils
  • Document date: 2017_10_25
    • ID: w85t4zz6_22
    Snippet: The primary function of CD62L, a vascular adhesion molecule, is directing neutrophil migration. In addition to CXCR1 and CXCR2, neutrophil migration requires the assistance of CD62L. In the present study, the expression of CD62L decreased following incubation with LPS for 4 h (Fig. 1C) , whereas n-butanol extract promoted the expression of CD62L in a dose-dependent manner (Fig. 2C ). This suggested that the extract promoted the migration of neutr.....
    Document: The primary function of CD62L, a vascular adhesion molecule, is directing neutrophil migration. In addition to CXCR1 and CXCR2, neutrophil migration requires the assistance of CD62L. In the present study, the expression of CD62L decreased following incubation with LPS for 4 h (Fig. 1C) , whereas n-butanol extract promoted the expression of CD62L in a dose-dependent manner (Fig. 2C ). This suggested that the extract promoted the migration of neutrophils by inhibiting the sepsis-induced downregulation of CD62L.

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