Author: Willemsen, Anouk; Zwart, Mark P
Title: On the stability of sequences inserted into viral genomes Document date: 2019_11_14
ID: vv5gpldi_46
Snippet: Here we illustrate how demography can affect the observed stability of an inserted sequence, using a simulation model. This model is based on (Willemsen et al. 2016 ) and incorporates logistic virus growth, deterministic recombination with a fixed rate, and population bottlenecks after a given number of generations. To describe virus growth and recombination in each generation, two coupled ordinary differential equations are used:.....
Document: Here we illustrate how demography can affect the observed stability of an inserted sequence, using a simulation model. This model is based on (Willemsen et al. 2016 ) and incorporates logistic virus growth, deterministic recombination with a fixed rate, and population bottlenecks after a given number of generations. To describe virus growth and recombination in each generation, two coupled ordinary differential equations are used:
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