Author: Willemsen, Anouk; Zwart, Mark P
Title: On the stability of sequences inserted into viral genomes Document date: 2019_11_14
ID: vv5gpldi_78
Snippet: Although the number of studies on insert stability in RT-dsDNA viruses is limited, we reason that several constraints limit insert stability in these viruses. Although small inserts will allow to track viral infection dynamics, the use of RT-dsDNA viruses for gene therapy does not seem practicable as integration into the host genome is a rare event for these viruses......
Document: Although the number of studies on insert stability in RT-dsDNA viruses is limited, we reason that several constraints limit insert stability in these viruses. Although small inserts will allow to track viral infection dynamics, the use of RT-dsDNA viruses for gene therapy does not seem practicable as integration into the host genome is a rare event for these viruses.
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