Selected article for: "mouse model and present study"
Author: LI, Xunliang; LI, Pengchong; CAO, Liyan; BAI, Yunyun; CHEN, Huijie; LIU, He; REN, Xiaofeng; LI, Guangxing
Title: Porcine IL-12 plasmid as an adjuvant improves the cellular and humoral immune responses of DNA vaccine targeting transmissible gastroenteritis virus spike gene in a mouse model
  • Document date: 2019_9_2
    • ID: rme6b022_6
    Snippet: In the present study, we constructed eukaryotic expression plasmids encoding the N-terminal fragment (2,106 bp) of the TGEV S protein (S1) and the porcine IL-12 (pIL-12) protein. We aimed to evaluate the potential of TGEV S1 as a DNA vaccine and pIL-12 as an adjuvant in a mouse model [3, 10] . Our results may lay the foundation for further studies on nucleic acid vaccines and immunological adjuvants......
    Document: In the present study, we constructed eukaryotic expression plasmids encoding the N-terminal fragment (2,106 bp) of the TGEV S protein (S1) and the porcine IL-12 (pIL-12) protein. We aimed to evaluate the potential of TGEV S1 as a DNA vaccine and pIL-12 as an adjuvant in a mouse model [3, 10] . Our results may lay the foundation for further studies on nucleic acid vaccines and immunological adjuvants.

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