Author: Neethirajan, Suresh; Ahmed, Syed Rahin; Chand, Rohit; Buozis, John; Nagy, Éva
Title: Recent Advances in Biosensor Development for Foodborne Virus Detection Document date: 2017_7_5
ID: sj6zfybb_73
Snippet: A polyethylene glycol (PEG) gold nanoparticle assay is used to detect human H3N2 influenza virus with α 2,6-thio-linked sialic acid derivative and synthesised thiolated trivalent [71] . A ratio of 75:25 of hemagglutinin to PEG ligand and trivalent α2,6-thio-linked sialic acid ligand is optimized by testing various ratios in the detection of non-purified influenza viruses. Importantly the assay can be used to differentiate human H3N2 and avian H.....
Document: A polyethylene glycol (PEG) gold nanoparticle assay is used to detect human H3N2 influenza virus with α 2,6-thio-linked sialic acid derivative and synthesised thiolated trivalent [71] . A ratio of 75:25 of hemagglutinin to PEG ligand and trivalent α2,6-thio-linked sialic acid ligand is optimized by testing various ratios in the detection of non-purified influenza viruses. Importantly the assay can be used to differentiate human H3N2 and avian H5N1 influenza viruses using trivalent thio-linked sialic acid ligands with the highly binding specificity as α2,6-binding and α2,3-binding, respectively.
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