Selected article for: "high dose and MERS cov"
Author: Lan, Jiaming; Yao, Yanfeng; Deng, Yao; Chen, Hong; Lu, Guangwen; Wang, Wen; Bao, Linlin; Deng, Wei; Wei, Qiang; Gao, George F.; Qin, Chuan; Tan, Wenjie
Title: Recombinant Receptor Binding Domain Protein Induces Partial Protective Immunity in Rhesus Macaques Against Middle East Respiratory Syndrome Coronavirus Challenge()
  • Document date: 2015_8_18
    • ID: q8i2gfut_43_1
    Snippet: creased. Furthermore, rRBD-immunised monkeys could not isolate MERS-CoV from the lungs while viral loads in the lungs and trachea of mock monkeys were as high as 50 and 100 TCID 50 /mL, respectively. Consistent with the results of immunity elicited by high and low dose of rRBD vaccine, the protection against MERS-CoV infection in monkey could be contributed to the humoral immune especially the neutralising antibodies rather than the cellular medi.....
    Document: creased. Furthermore, rRBD-immunised monkeys could not isolate MERS-CoV from the lungs while viral loads in the lungs and trachea of mock monkeys were as high as 50 and 100 TCID 50 /mL, respectively. Consistent with the results of immunity elicited by high and low dose of rRBD vaccine, the protection against MERS-CoV infection in monkey could be contributed to the humoral immune especially the neutralising antibodies rather than the cellular mediated immunity.

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