Selected article for: "cell line and disseminated disease"

Title: Research Communications of the 24th ECVIM-CA Congress
  • Document date: 2015_1_10
  • ID: r59usk02_296
    Snippet: No conflicts of interest reported. Histiocytic sarcoma (HS) is a neoplastic proliferation of interstitial dendritic cells or tissue macrophages. Dogs with HS can present with local disease or with multifocal (disseminated) involvement. Disseminated HS is poorly responsive to therapy and almost always fatal. Little is established regarding the aetio-pathology of histiocytic sarcoma in dogs. The purpose of this study was to establish and characteri.....
    Document: No conflicts of interest reported. Histiocytic sarcoma (HS) is a neoplastic proliferation of interstitial dendritic cells or tissue macrophages. Dogs with HS can present with local disease or with multifocal (disseminated) involvement. Disseminated HS is poorly responsive to therapy and almost always fatal. Little is established regarding the aetio-pathology of histiocytic sarcoma in dogs. The purpose of this study was to establish and characterise a HS cell line from fresh tumour samples obtained from a dog with disseminated HS in order to further clarify disease pathogenesis and behaviour.

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