Title: Research Communications of the 24th ECVIM-CA Congress Document date: 2015_1_10
ID: r59usk02_551
Snippet: For validation, serum samples were spiked at low (0.017 mg/ mL), medium (0.27 mg/mL) and high (2.16 mg/mL) iohexol concentrations. They were analysed, along with standard calibration curves (8 concentrations ranging from 0.017 to 2.16 mg/mL), using deltaDOT's Label-Free high performance capillary electrophoresis (HPCE) system. Data were analysed using deltaDOT's General Separation Transform (GST). Clinical and spiked serum samples were also sent .....
Document: For validation, serum samples were spiked at low (0.017 mg/ mL), medium (0.27 mg/mL) and high (2.16 mg/mL) iohexol concentrations. They were analysed, along with standard calibration curves (8 concentrations ranging from 0.017 to 2.16 mg/mL), using deltaDOT's Label-Free high performance capillary electrophoresis (HPCE) system. Data were analysed using deltaDOT's General Separation Transform (GST). Clinical and spiked serum samples were also sent for analysis by mass spectrometry (MS) at a reference laboratory (14 samples for comparison). Concentrations obtained by HPCE and MS were compared in a Bland Altman plot. GFR for clinical samples was calculated from the measured iohexol concentrations using the method reported by Bexfield (2008) .
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