Selected article for: "plasma concentration and study aim"
Title: Research Communications of the 27(th) ECVIM-CA Congress: Intercontinental, Saint Julian's, Malta, 14th to 16th September 2017
  • Document date: 2017_11_7
    • ID: roslkxeq_207
    Snippet: The aim of this study was to evaluate whether a TRH stimulation test can differentiate between dogs with NTI and dogs with hypothyroidism that have a plasma TSH concentration within the reference range, by measuring plasma concentrations of GH and TSH. 21 dogs with clinical signs consistent with hypothyroidism, a plasma TT4 concentration below the reference interval (19-46 nmol/L), and a plasma TSH concentration within the reference interval (<0......
    Document: The aim of this study was to evaluate whether a TRH stimulation test can differentiate between dogs with NTI and dogs with hypothyroidism that have a plasma TSH concentration within the reference range, by measuring plasma concentrations of GH and TSH. 21 dogs with clinical signs consistent with hypothyroidism, a plasma TT4 concentration below the reference interval (19-46 nmol/L), and a plasma TSH concentration within the reference interval (<0.60 µg/L) were included in this study. Thyroid scintigraphy was performed to classify dogs as having hypothyroidism or NTI. All dogs underwent a TRH stimulation test in which plasma concentrations of TSH and GH were measured twice before intravenous administration of 10 µg/kg TRH (t = À15 and t = 0) and 30 and 45 min after TRH administration.

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